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Hepatitis B virus can be prevented if the use of vaccines early and properly regulated. The World Health Organization recommends that all children should receive hepatitis B vaccination. for children in the area have the rate of hepatitis B virus infection is high, should be vaccinated within 24 hours after birth and the following dose according to the immunization schedule. Although hepatitis B prevention may be, the rate of coverage of hepatitis B vaccine worldwide achieve 75% lower than goal is 90% which proportion of the hepatitis B vaccine birth dose (within first 24 hours) new hit 27%. Moreover, according to estimates by the World Health Organization, approximately 240 million people worldwide have chronic hepatitis B virus infection and chronic disease burden caused by hepatitis B causes for the health system as well as the health of the people was great.
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